Injectable vs. Non-Injectable Mesotherapy: Which is Right for Your Practice?

Mesotherapy is a cornerstone of modern aesthetic treatments, offering targeted, effective solutions to skin aging, dehydration, dullness, and more. With both injectable and non-injectable modalities available, understanding the differences is essential to choosing the right approach for your patients and your practice.

What Is Mesotherapy?

Mesotherapy is a technique designed to deliver active ingredients — such as hyaluronic acid, peptides, vitamins, amino acids, and antioxidants — into the skin where they can stimulate regeneration and repair. This can be achieved through microinjections or advanced transdermal delivery systems.

Injectable Mesotherapy

How it works:
Tiny injections deliver actives directly into the dermis using needles or mechanical devices.

Benefits:

  • Deep, targeted delivery

  • Rapid, visible results

  • Highly customizable for specific skin concerns

Limitations:

  • Requires a licensed medical professional

  • Potential discomfort, bruising, or downtime

  • Invasive nature may deter some patients

Non-Injectable Mesotherapy

How it works:
Using devices such as dermapens, microneedling, electroporation, or TDS (Transdermal Delivery Systems), ingredients are pushed into the skin without needles.

Benefits:

  • Needle-free and pain-free

  • No downtime — ideal for busy lifestyles

  • Suitable for sensitive skin and preventative care

  • Can be used in aesthetic clinics without medical licensing

Limitations:

  • Penetration is more superficial

  • Results may take longer and require repeated sessions

Introducing the Origen Collection by ProMirall

At ProMirall, we are proud to offer Origen, our signature collection of monodose professional skincare solutions designed specifically for non-injectable mesotherapy.

Formulated with pharmaceutical-grade ingredients and developed for protocols using microneedling, dermapen, and TDS systems, Origen delivers visible results in terms of radiance, revitalization, and firmness — all without the use of needles.

Each formula in the Origen line is:

  • Sterile and single-use, ensuring maximum safety and hygiene

  • Designed to complement advanced cosmetic procedures

  • Backed by scientific research and dermatological expertise

Whether you are just starting with mesotherapy or expanding your treatment offering, Origen offers an effective, easy-to-integrate option with professional-grade performance.

Looking ahead?
We are also exploring the development of injectable mesotherapy solutions in the near future. For partners with clear forecasts and market demand, we are open to building future collaborations in this segment.

Discover Origen and elevate your mesotherapy protocols

Explore our range at www.promirall.com or contact us for more details and distribution opportunities.

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The Power of Regeneration- PDRN